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RUVBL1 Monoclonal antibody, PBS Only

RUVBL1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F2D9

Cat no : 67750-1-PBS

Print datasheet

Synonyms

49 kDa TBP interacting protein, ECP 54, ECP54, INO80 complex subunit H, INO80H, Nuclear matrix protein 238, PONTIN, Pontin 52, Pontin52, RuvB like 1, RuvB like 1 (E. coli), RUVBL1, RVB1, TAP54 alpha, TIH1, TIP49, TIP49A

验证数据展示

  • WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67750-1-Ig (RUVBL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67750-1-PBS in a different storage buffer formulation.

  • WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67750-1-Ig (RUVBL1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67750-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy RUVBL1 Ready-To-Use IHC Kit. RUVBL1 primary antibody included.

产品信息

67750-1-PBS targets RUVBL1 in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, rat
Immunogen RUVBL1 fusion protein Ag16688 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name RuvB-like 1 (E. coli)
Synonyms 49 kDa TBP interacting protein, ECP 54, ECP54, INO80 complex subunit H, INO80H, Nuclear matrix protein 238, PONTIN, Pontin 52, Pontin52, RuvB like 1, RuvB like 1 (E. coli), RUVBL1, RVB1, TAP54 alpha, TIH1, TIP49, TIP49A
Calculated Molecular Weight 456 aa, 50 kDa
Observed Molecular Weight50 kDa
GenBank Accession NumberBC002993
Gene Symbol RUVBL1
Gene ID (NCBI) 8607
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y265
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RUVBL1 is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis[PMID: 21617703]. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. RUVBL1 is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme. RUVBL1 is also highly homologous to RuvB proteins that function as a DNA helicase promote branch migration of the Holliday junction[PMID: 9588198].