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SCN3B Recombinant antibody, PBS Only

SCN3B Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, rat, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

230316F8

Cat no : 82959-1-PBS

Print datasheet

Synonyms

Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396

验证数据展示

  • WB analysis using 82959-1-RR (same clone as 82959-1-PBS)

    WB analysis using 82959-1-RR (same clone as 82959-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82959-1-RR (SCN3B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82959-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82959-1-PBS

    Affinity and Kinetic Characterization of 82959-1-PBS

    Biolayer interferometry (BLl) kinetic assays of 82959-1-RR against Human SCN3B were performed. The affinity constant is 0.429 nM.

产品信息

82959-1-PBS targets SCN3B in WB, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, rat, mouse
Immunogen SCN3B fusion protein Ag23201 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name sodium channel, voltage-gated, type III, beta
Synonyms Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396
Observed Molecular Weight29 kDa
GenBank Accession NumberBC126265
Gene Symbol SCN3B
Gene ID (NCBI) 55800
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NY72
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The sodium voltage-gated channel beta subunit 3 (SCN3B) plays a crucial role in electrically excitable cells and conduction tissue in the heart. Some previous studies have established that genetic modification in sodium voltage-channel genes encoding for the cardiac β-subunits, such as SCN1B, SCN2B, SCN3B and SCN4B, can result in atrial fibrillation (AF). (PMID: 36362949)