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SCN3B Recombinant antibody

SCN3B Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, rat, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

230316F8

Cat no : 82959-1-RR

Print datasheet

Synonyms

Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396

验证数据展示

  • WB analysis using 82959-1-RR

    WB analysis using 82959-1-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 82959-1-RR (SCN3B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 82959-1-RR

    Affinity and Kinetic Characterization of 82959-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82959-1-RR against Human SCN3B were performed. The affinity constant is 0.429 nM.

经过测试的应用

Positive WB detected inHEK-293 cells, rat brain tissue, mouse brain tissue, fetal human brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

82959-1-RR targets SCN3B in WB, ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human, rat, mouse
Immunogen SCN3B fusion protein Ag23201 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name sodium channel, voltage-gated, type III, beta
Synonyms Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396
Observed Molecular Weight29 kDa
GenBank Accession NumberBC126265
Gene Symbol SCN3B
Gene ID (NCBI) 55800
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NY72
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The sodium voltage-gated channel beta subunit 3 (SCN3B) plays a crucial role in electrically excitable cells and conduction tissue in the heart. Some previous studies have established that genetic modification in sodium voltage-channel genes encoding for the cardiac β-subunits, such as SCN1B, SCN2B, SCN3B and SCN4B, can result in atrial fibrillation (AF). (PMID: 36362949)

实验方案

Product Specific Protocols
WB protocol for SCN3B antibody 82959-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols