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验证数据展示

  • WB analysis using 67088-1-Ig (same clone as 67088-1-PBS)

    WB analysis using 67088-1-Ig (same clone as 67088-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67088-1-Ig (SDC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 67088-1-Ig (same clone as 67088-1-PBS)

    IHC staining of human liver cancer using 67088-1-Ig (same clone as 67088-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

SDC2 Monoclonal antibody, PBS Only

SDC2 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67088-1-PBS

产品说明书

CloneNo. 3A7B2

宿主/亚型

Mouse / IgG2a

种属反应性

Human

应用

WB, IHC, Indirect ELISA

别名

Fibroglycan, HSPG, HSPG1, SDC2, SYND2, syndecan 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67088-1-PBS targets SDC2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 SDC2 fusion protein Ag5739 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 syndecan 2
别名 Fibroglycan, HSPG, HSPG1, SDC2, SYND2, syndecan 2
计算分子量 22 kDa
观测分子量 19 kDa, 22 and 48 kDa
GenBank蛋白编号BC049836
基因名称 SDC2
Gene ID (NCBI) 6383
RRIDAB_2882395
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP34741
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SDC2, containing cell surface heparan sulphate proteoglycan, functions as an integral membrane protein and participates in cell proliferation, cell migration, cell adhesion and signal transduction. It has been reported that the expression level of SDC2 will be up-regulated under hypoxia condition which can induce increased release of cytokines and chemokines. Besides, methylated SDC2 can be used as a potential biomarker for early diagnosis of colon cancer. 67088-1-Ig antibody detects the 19 and 22 kDa SDC2 isoforms as well as the 48 kDa dimeric protein in SDS-PAGE.(PMID: 18803305, 23297089, 30022330, 29945573)