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SDC2 Monoclonal antibody, PBS Only

SDC2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3A7B2

Cat no : 67088-1-PBS

Print datasheet

Synonyms

Fibroglycan, HSPG, HSPG1, SDC2, SYND2, syndecan 2

验证数据展示

  • WB analysis using 67088-1-Ig (same clone as 67088-1-PBS)

    WB analysis using 67088-1-Ig (same clone as 67088-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67088-1-Ig (SDC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 67088-1-Ig (same clone as 67088-1-PBS)

    IHC staining of human liver cancer using 67088-1-Ig (same clone as 67088-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

产品信息

67088-1-PBS targets SDC2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen SDC2 fusion protein Ag5739 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name syndecan 2
Synonyms Fibroglycan, HSPG, HSPG1, SDC2, SYND2, syndecan 2
Calculated Molecular Weight 22 kDa
Observed Molecular Weight 19 kDa, 22 and 48 kDa
GenBank Accession NumberBC049836
Gene Symbol SDC2
Gene ID (NCBI) 6383
RRIDAB_2882395
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP34741
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SDC2, containing cell surface heparan sulphate proteoglycan, functions as an integral membrane protein and participates in cell proliferation, cell migration, cell adhesion and signal transduction. It has been reported that the expression level of SDC2 will be up-regulated under hypoxia condition which can induce increased release of cytokines and chemokines. Besides, methylated SDC2 can be used as a potential biomarker for early diagnosis of colon cancer. 67088-1-Ig antibody detects the 19 and 22 kDa SDC2 isoforms as well as the 48 kDa dimeric protein in SDS-PAGE.(PMID: 18803305, 23297089, 30022330, 29945573)