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×
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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67352-1-Ig (same clone as 67352-1-PBS)

    WB analysis using 67352-1-Ig (same clone as 67352-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67352-1-Ig (SEC63 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67352-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 67352-1-Ig (same clone as 67352-1-PBS)

    IF Staining of HEK-293 using 67352-1-Ig (same clone as 67352-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HEK-293 cells using SEC63 antibody (67352-1-Ig, Clone: 1C10E1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67352-1-PBS in a different storage buffer formulation.

SEC63 Monoclonal antibody, PBS Only

SEC63 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 67352-1-PBS

产品说明书

CloneNo. 1C10E1

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, IF/ICC, ELISA

别名

ERdj2, PRO2507, SEC63, SEC63 homolog (S. cerevisiae), SEC63L

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67352-1-PBS targets SEC63 in WB, IF/ICC, ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 Human
免疫原 SEC63 fusion protein Ag5783 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 SEC63 homolog (S. cerevisiae)
别名 ERdj2, PRO2507, SEC63, SEC63 homolog (S. cerevisiae), SEC63L
计算分子量 88 kDa
观测分子量 90 kDa
GenBank蛋白编号BC047221
基因名称 SEC63
Gene ID (NCBI) 11231
RRIDAB_2882608
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9UGP8
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SEC63 is a integral ER membrane protein. SEC63 and SEC62 form a dimeric complex and play a central role in translocation of nascent and newly synthesized precursor polypeptides into the ER. Mutations in the gene encoding SEC63 cause polycystic liver disease in humans. The intact SEC63 protein is usually detected around 83-90 kDa, while smaller cleavage products can be observed by autophagy proteolysis (PMID: 25052096)