验证数据展示
产品信息
67397-1-PBS targets SEMA7A in WB, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | SEMA7A fusion protein Ag28804 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
别名 | CD108, CDw108, H SEMA K1, H Sema L, JMH, JMH blood group antigen, Sema K1, Sema L, SEMA7A, SEMAK1, SEMAL, Semaphorin 7A, Semaphorin K1, Semaphorin L |
计算分子量 | 666 aa, 75 kDa |
观测分子量 | 75-80 kDa |
GenBank蛋白编号 | BC101643 |
基因名称 | SEMA7A |
Gene ID (NCBI) | 8482 |
RRID | AB_2882640 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O75326 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SEMA7A, also named CD108 and SEMAL, belongs to the semaphorin family. SEMA7A is the only membrane‐associated glycosylphosphatidylinositol (GPI)‐linked semaphorin and plays a role in the regulation of neuronal axon outgrowth. In addition to its role in guiding axon pathfinding during neuronal development, Sema7A has diverse functions in morphogenesis and immune cell control and regulates T cell responses via the α1β1 integrin receptor (PMID: 31179640). SEMA7A has 2 isoforms with molecular weights of 73 and 75 kDa, respectively.