SERPING1 Recombinant antibody, PBS Only
SERPING1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3H7
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy SERPING1 Ready-To-Use IHC Kit. SERPING1 primary antibody included.
产品信息
82731-1-PBS targets SERPING1 in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | Human |
Immunogen | SERPING1 fusion protein Ag2819 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
Synonyms | C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1 |
Calculated Molecular Weight | 500 aa, 55 kDa |
Observed Molecular Weight | 100 kDa |
GenBank Accession Number | BC011171 |
Gene Symbol | SERPING1 |
Gene ID (NCBI) | 710 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P05155 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein. Of its 95-105 kDa apparent molecular mass, the protein moiety of 500 aa accounts for only 55 kDa. The native 105 kDa form of C1INH could be cleaved into 60-65 kDa fragments.