SERPING1 Recombinant antibody

SERPING1 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

3H7

Cat no : 82731-1-RR

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Synonyms

C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1



经过测试的应用

Positive WB detected inhuman plasma
Planning an IHC experiment? We recommend our IHCeasy SERPING1 Ready-To-Use IHC Kit. SERPING1 primary antibody included.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

82731-1-RR targets SERPING1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity Human
Immunogen SERPING1 fusion protein Ag2819 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Synonyms C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1
Calculated Molecular Weight 500 aa, 55 kDa
Observed Molecular Weight 100 kDa
GenBank Accession NumberBC011171
Gene Symbol SERPING1
Gene ID (NCBI) 710
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP05155
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein. Of its 95-105 kDa apparent molecular mass, the protein moiety of 500 aa accounts for only 55 kDa. The native 105 kDa form of C1INH could be cleaved into 60-65 kDa fragments.

实验方案

Product Specific Protocols
WB protocol for SERPING1 antibody 82731-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols