验证数据展示
产品信息
66882-1-PBS targets SERPING1/C1 Inactivator in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, pig, rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, pig, rat |
免疫原 | SERPING1/C1 Inactivator fusion protein Ag16782 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
别名 | C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1, SERPING1/C1 Inactivator |
计算分子量 | 500 aa, 55 kDa |
观测分子量 | 100 kDa |
GenBank蛋白编号 | BC011171 |
基因名称 | SERPING1 |
Gene ID (NCBI) | 710 |
RRID | AB_2882214 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P05155 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein.