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- KD/KO Validated
SERPING1/C1 Inactivator Monoclonal antibody
SERPING1/C1 Inactivator Monoclonal Antibody for WB, IF/ICC, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, pig, rat and More (1)
Applications
WB, IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
1B11B11
验证数据展示
经过测试的应用
| Positive WB detected in | human plasma tissue, human plasma, pig plasma, rat serum |
| Positive IF/ICC detected in | HeLa cells, HepG2 cells |
Planning an IHC experiment? We recommend our IHCeasy SERPING1 Ready-To-Use IHC Kit. SERPING1 primary antibody included.
Planning an IF experiment? We recommend our CoraLite®594 conjugated versions of this antibody.
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:8000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:400-1:1600 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
产品信息
66882-1-Ig targets SERPING1/C1 Inactivator in WB, IF/ICC, ELISA applications and shows reactivity with Human, pig, rat samples.
| Tested Applications | WB, IF/ICC, ELISA Application Description |
| Cited Applications | WB |
| Tested Reactivity | Human, pig, rat |
| Cited Reactivity | human |
| Immunogen | SERPING1/C1 Inactivator fusion protein Ag16782 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| Synonyms | C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1, SERPING1/C1 Inactivator |
| Calculated Molecular Weight | 500 aa, 55 kDa |
| Observed Molecular Weight | 100 kDa |
| GenBank Accession Number | BC011171 |
| Gene Symbol | SERPING1 |
| Gene ID (NCBI) | 710 |
| RRID | AB_2882214 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P05155 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SERPING1/C1 Inactivator antibody 66882-1-Ig | Download protocol |
| IF protocol for SERPING1/C1 Inactivator antibody 66882-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
iScience Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
|
