验证数据展示
经过测试的应用
Positive IF/ICC detected in | HeLa cells |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-66882 targets SERPING1/C1 Inactivator in IF/ICC applications and shows reactivity with Human, pig, rat samples.
经测试应用 | IF/ICC Application Description |
经测试反应性 | Human, pig, rat |
免疫原 | SERPING1/C1 Inactivator fusion protein Ag16782 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
别名 | C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1 |
计算分子量 | 500 aa, 55 kDa |
观测分子量 | 100 kDa |
GenBank蛋白编号 | BC011171 |
基因名称 | SERPING1 |
Gene ID (NCBI) | 710 |
RRID | AB_2934747 |
偶联类型 | CoraLite®594 Fluorescent Dye |
最大激发/发射波长 | 588 nm / 604 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P05155 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein.
实验方案
Product Specific Protocols | |
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IF protocol for CL594 SERPING1/C1 Inactivator antibody CL594-66882 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |