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验证数据展示

  • IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

    IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

    IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

SFRP5 Polyclonal antibody, PBS Only

SFRP5 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 19177-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

19177-1-PBS targets SFRP5 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SFRP5 fusion protein Ag5715 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 secreted frizzled-related protein 5
别名
计算分子量 36 kDa
GenBank蛋白编号BC050435
基因名称 SFRP5
Gene ID (NCBI) 6425
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ5T4F7
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine whose expression is perturbed in models of obesity and type 2 diabetes. SFRP5 is secreted by adipocytes and that it controls the micro-environment of white adipose tissue under conditions of metabolic stress (PMID: 20558665). SFRP5 gene consists of 317 amino acid residues and 3 coding exons and maps to chromosome 10q24.1 in humans. SFRP5 was initially found to be highly expressed in retinal pigment epithelium cells and moderately expressed in the pancreas. SFRP5 is involved in the pathological process of obesity, insulin resistance, dyslipidemia, inflammation, and fibrosis and is associated with obesity, T2D, and ASCVD (PMID: 31199714, PMID: 32004418).