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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of mouse brain using 67841-1-Ig (same clone as 67841-1-PBS)

    WB analysis of mouse brain using 67841-1-Ig (same clone as 67841-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 67841-1-Ig (SH3BP5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67841-1-PBS in a different storage buffer formulation.

  • WB analysis of chicken brain using 67841-1-Ig (same clone as 67841-1-PBS)

    WB analysis of chicken brain using 67841-1-Ig (same clone as 67841-1-PBS)

    chicken brain tissue were subjected to SDS PAGE followed by western blot with 67841-1-Ig (SH3BP5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67841-1-PBS in a different storage buffer formulation.

  • WB analysis using 67841-1-Ig (same clone as 67841-1-PBS)

    WB analysis using 67841-1-Ig (same clone as 67841-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67841-1-Ig (SH3BP5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67841-1-PBS in a different storage buffer formulation.

SH3BP5 Monoclonal antibody, PBS Only

SH3BP5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67841-1-PBS
CloneNo. 1B9D4

Host / Isotype

Mouse / IgG1

Reactivity

Human, rabbit, mouse, rat, pig, chicken

Applications

WB, Indirect ELISA

Synonyms

SAB, SH3 domain binding protein 5, SH3BP 5, SH3BP5

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

67841-1-PBS targets SH3BP5 in WB, Indirect ELISA applications and shows reactivity with Human, rabbit, mouse, rat, pig, chicken samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, rabbit, mouse, rat, pig, chicken
Immunogen SH3BP5 fusion protein Ag30252 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name SH3-domain binding protein 5 (BTK-associated)
Synonyms SAB, SH3 domain binding protein 5, SH3BP 5, SH3BP5
Calculated Molecular Weight 47 kDa
Observed Molecular Weight75 kDa
GenBank Accession NumberBC010123
Gene Symbol SH3BP5
Gene ID (NCBI) 9467
RRIDAB_2918603
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO60239
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SH3BP5(SH3 domain-binding protein 5) is also named as SAB. It is previously isolated in a screen for proteins capable of binding to the Src homology 3 (SH3) domain of Bruton's tyrosine kinase (Btk) and could play a role in targeting JNK and Btk to mitochondria and/or mediating cross-talk between the JNK and Btk signalling pathways. It has 2 isoforms produced by alternative splicing with the molecular mass of 50 kDa and 32 kDa. There are two bands of 83 kDa and 70 kDa can be detected in A431 and the larger species may correspond to splice variants of SH3BP5 or SH3BP5 proteins that have undergone post-translational modification(PMID:12167088). In addition, we detect the band of 32 kDa as the isoform 2 of SH3BP5 and another band of 62 kDa besides the 47 kDa and 80 kDa.