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SHARPIN Monoclonal antibody, PBS Only

SHARPIN Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3A9E2

Cat no : 67177-1-PBS

Print datasheet

Synonyms

DKFZp434N1923, hSIPL1, SHARPIN, SIPL1

验证数据展示

  • WB analysis using 67177-1-Ig (same clone as 67177-1-PBS)

    WB analysis using 67177-1-Ig (same clone as 67177-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67177-1-Ig (SHARPIN antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67177-1-PBS in a different storage buffer formulation.

产品信息

67177-1-PBS targets SHARPIN in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen SHARPIN fusion protein Ag6367 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name SHANK-associated RH domain interactor
Synonyms DKFZp434N1923, hSIPL1, SHARPIN, SIPL1
Calculated Molecular Weight 40 kDa
Observed Molecular Weight 40 kDa
GenBank Accession NumberBC025244
Gene Symbol SHARPIN
Gene ID (NCBI) 81858
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9H0F6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SHARPIN is as a third component of the linear ubiquitin chain assembly complex (LUBAC), recruited to the CD40 and TNF receptor signaling complexes together with its other constituents, HOIL1 and HOIP(PMID:21455173).SHARPIN is enriched in the postsynaptic density and forms a complex with SHANK in heterologous cells and brain(PMID:11178875).It has 2 isoforms produced by alternative splicing.