验证数据展示
产品信息
67177-1-PBS targets SHARPIN in WB, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | SHARPIN fusion protein Ag6367 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | SHANK-associated RH domain interactor |
别名 | DKFZp434N1923, hSIPL1, SHARPIN, SIPL1 |
计算分子量 | 40 kDa |
观测分子量 | 40 kDa |
GenBank蛋白编号 | BC025244 |
基因名称 | SHARPIN |
Gene ID (NCBI) | 81858 |
RRID | AB_2882473 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9H0F6 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SHARPIN is as a third component of the linear ubiquitin chain assembly complex (LUBAC), recruited to the CD40 and TNF receptor signaling complexes together with its other constituents, HOIL1 and HOIP(PMID:21455173).SHARPIN is enriched in the postsynaptic density and forms a complex with SHANK in heterologous cells and brain(PMID:11178875).It has 2 isoforms produced by alternative splicing.