CoraLite® Plus 750-conjugated SHBG Recombinant antibody
SHBG Uni-rAbTM Recombinant Antibody for WB
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB
Conjugate
CoraLite® Plus 750 Fluorescent Dye
CloneNo.
230356F10
验证数据展示
经过测试的应用
| Positive WB detected in | human plasma |
For other applications, we recommend the unconjugated version of this antibody, 83096-1-PBS
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL750-83096 targets SHBG in WB applications and shows reactivity with Human samples.
| Tested Applications | WB Application Description |
| Tested Reactivity | Human |
| Immunogen | Recombinant protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | sex hormone-binding globulin |
| Synonyms | ABP, SBP, sex hormone binding globulin, Sex steroid binding protein, SHBG, TEBG |
| Calculated Molecular Weight | 402 aa, 44 kDa |
| Observed Molecular Weight | 40-50 kDa |
| GenBank Accession Number | BC101785 |
| Gene Symbol | SHBG |
| Gene ID (NCBI) | 6462 |
| Conjugate | CoraLite® Plus 750 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 755 nm / 780 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P04278 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SHBG (sex hormone-binding globulin), also known as androgen-binding protein (ABP), is the specific transport protein for sex steroid hormones in humans. SHBG is synthesized mainly by the liver and circulates in the blood, in form of homodimer with a single steroid-binding site per dimer. In addition to the plasma SHBG, a testis isoform expressed by Sortoli cells also exists due to the gene alternative splicing. Various bands (44-56 kDa) recognized by this antibody may represent variably glycosylated or different isoforms of SHBG.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for CL Plus 750 SHBG antibody CL750-83096 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |