• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67194-2-Ig (same clone as 67194-2-PBS)

    WB analysis using 67194-2-Ig (same clone as 67194-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67194-2-Ig (SHC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67194-2-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50763-1

    Cytometric bead array standard curve of MP50763-1

    Cytometric bead array standard curve of MP50763-1, SHC1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67194-2-PBS. Detection antibody: 67194-3-PBS. Standard:Ag25173. Range: 0.098-100 ng/mL.

  • Cytometric bead array standard curve of MP50763-3

    Cytometric bead array standard curve of MP50763-3

    Cytometric bead array standard curve of MP50763-3, SHC1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67194-2-PBS. Detection antibody: 67194-4-PBS. Standard:Ag25173. Range: 0.391-50 ng/mL.

SHC1 Monoclonal antibody, PBS Only (Capture)

SHC1 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 67194-2-PBS
CloneNo. 1A5B1

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

SHC, SHC-transforming protein 3, SHC-transforming protein 1, SHC transforming protein 1, SH2 domain protein C1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

67194-2-PBS targets SHC1 as part of a matched antibody pair:

MP50763-1: 67194-2-PBS capture and 67194-3-PBS detection (validated in Cytometric bead array)

MP50763-3: 67194-2-PBS capture and 67194-4-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications WB, Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen SHC1 fusion protein Ag25173 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name SHC (Src homology 2 domain containing) transforming protein 1
Synonyms SHC, SHC-transforming protein 3, SHC-transforming protein 1, SHC transforming protein 1, SH2 domain protein C1
Calculated Molecular Weight 63 kDa
Observed Molecular Weight66 kDa
GenBank Accession NumberNM_183001
Gene Symbol SHC1
Gene ID (NCBI) 6464
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP29353
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The proto-oncogene SHC family consists of SHCA, SHCB, SHCC, and SHCD4 gene members, which can encode 7 kinds of cohesive molecules. SHC family is widely expressed and functional. The SHC1 gene is located in zone 1, region 2 of human chromosome 1. SHC1 is believed to be involved in inhibiting neuronal apoptosis and regulating the receptor tyrosine kinase pathway. SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.