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验证数据展示

  • WB analysis using 67194-2-Ig (same clone as 67194-2-PBS)

    WB analysis using 67194-2-Ig (same clone as 67194-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67194-2-Ig (SHC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67194-2-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50763-1

    Cytometric bead array standard curve of MP50763-1

    Cytometric bead array standard curve of MP50763-1, SHC1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67194-2-PBS. Detection antibody: 67194-3-PBS. Standard:Ag25173. Range: 0.098-100 ng/mL.

  • Cytometric bead array standard curve of MP50763-3

    Cytometric bead array standard curve of MP50763-3

    Cytometric bead array standard curve of MP50763-3, SHC1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67194-2-PBS. Detection antibody: 67194-4-PBS. Standard:Ag25173. Range: 0.391-50 ng/mL.

SHC1 Monoclonal antibody, PBS Only (Capture)

SHC1 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 67194-2-PBS

产品说明书

CloneNo. 1A5B1

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA

别名

SHC, SHC-transforming protein 3, SHC-transforming protein 1, SHC transforming protein 1, SH2 domain protein C1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67194-2-PBS targets SHC1 as part of a matched antibody pair:

MP50763-1: 67194-2-PBS capture and 67194-3-PBS detection (validated in Cytometric bead array)

MP50763-3: 67194-2-PBS capture and 67194-4-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 SHC1 fusion protein Ag25173 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 SHC (Src homology 2 domain containing) transforming protein 1
别名 SHC, SHC-transforming protein 3, SHC-transforming protein 1, SHC transforming protein 1, SH2 domain protein C1
计算分子量 63 kDa
观测分子量66 kDa
GenBank蛋白编号NM_183001
基因名称 SHC1
Gene ID (NCBI) 6464
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP29353
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The proto-oncogene SHC family consists of SHCA, SHCB, SHCC, and SHCD4 gene members, which can encode 7 kinds of cohesive molecules. SHC family is widely expressed and functional. The SHC1 gene is located in zone 1, region 2 of human chromosome 1. SHC1 is believed to be involved in inhibiting neuronal apoptosis and regulating the receptor tyrosine kinase pathway. SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.