• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68647-1-Ig (same clone as 68647-1-PBS)

    WB analysis using 68647-1-Ig (same clone as 68647-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68647-1-Ig (SHCBP1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68647-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 68647-1-Ig (same clone as 68647-1-PBS)

    IHC staining of human liver cancer using 68647-1-Ig (same clone as 68647-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 68647-1-Ig (SHCBP1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68647-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 68647-1-Ig (same clone as 68647-1-PBS)

    IHC staining of human liver cancer using 68647-1-Ig (same clone as 68647-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 68647-1-Ig (SHCBP1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68647-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 68647-1-Ig (same clone as 68647-1-PBS)

    IF Staining of HEK-293 using 68647-1-Ig (same clone as 68647-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using SHCBP1 antibody (68647-1-Ig, Clone: 1B2E12 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 68647-1-PBS in a different storage buffer formulation.

SHCBP1 Monoclonal antibody, PBS Only

SHCBP1 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 68647-1-PBS

CloneNo.

1B2E12

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

SHC SH2 domain-binding protein 1, PAL

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

68647-1-PBS targets SHCBP1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SHCBP1 fusion protein Ag17517 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name SHC SH2-domain binding protein 1
Synonyms SHC SH2 domain-binding protein 1, PAL
Calculated Molecular Weight 672 aa, 76 kDa
Observed Molecular Weight76 kDa
GenBank Accession NumberBC030699
Gene Symbol SHCBP1
Gene ID (NCBI) 79801
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ8NEM2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SHCBP1 was initially identified as a potential gene associated with cell proliferation in fibroblasts. SHCBP1 exerts a crucial physiological function in normal tissue development. Chen et al. showed that SHCBP1 is an essential component of FGF signaling in neural progenitor cells. SHCBP1 is also upregulated during T cell proliferation and regulates CD4+ T cell effector function in vivo. Recently, SHCBP1 was shown to be closely associated with cancer development.