验证数据展示
产品信息
66367-1-PBS targets SKAP2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, pig, rat, mouse samples.
Tested Applications | WB, IHC, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human, pig, rat, mouse |
Immunogen | SKAP2 fusion protein Ag3615 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | src kinase associated phosphoprotein 2 |
Synonyms | PRAP, Pyk2/RAFTK associated protein, RA70, SAPS, SCAP2, SKAP 55HOM, SKAP HOM, SKAP2, SKAP55 homolog, SKAP55R |
Calculated Molecular Weight | 41 kDa |
Observed Molecular Weight | 55 kDa |
GenBank Accession Number | BC036044 |
Gene Symbol | SKAP2 |
Gene ID (NCBI) | 8935 |
RRID | AB_2881747 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | O75563 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SKAP2 (src kinase associated phosphoprotein 2), also named PRAP, contains PH domain and SH3 domain. It is localized in cytoplasm and was expressed in ubiquitously in various tissues including lung, skeletal muscle, and spleen, but not detectable in thymus and T cell lymphoma cells. SKAP2 may negatively regulate alpha-synuclein phosphorylation following cell stress. SKAP2 may be involved in B-cell and macrophage adhesion processes by coupling the B-cell receptor (BCR) to integrin activation.