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SKIV2L Monoclonal antibody, PBS Only

SKIV2L Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A9G2

Cat no : 68547-1-PBS

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Synonyms

170A, DDX13, Helicase like protein, Helicase SKI2W, HLP, SKI2, SKI2W, SKIV2, SKIV2L, W

验证数据展示

  • WB analysis using 68547-1-Ig (same clone as 68547-1-PBS)

    WB analysis using 68547-1-Ig (same clone as 68547-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68547-1-Ig (SKIV2L antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68547-1-PBS in a different storage buffer formulation.

产品信息

68547-1-PBS targets SKIV2L in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen SKIV2L fusion protein Ag33679 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name superkiller viralicidic activity 2-like (S. cerevisiae)
Synonyms 170A, DDX13, Helicase like protein, Helicase SKI2W, HLP, SKI2, SKI2W, SKIV2, SKIV2L, W
Calculated Molecular Weight 1246 aa, 138 kDa
Observed Molecular Weight138-145 kDa
GenBank Accession NumberBC015758
Gene Symbol SKIV2L
Gene ID (NCBI) 6499
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ15477
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The Ski complex is a multiprotein complex required for exosome-mediated RNA surveillance, including the regulation of normal mRNA and the decay of nonfunctional mRNA. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) [PMID:22444670]. SKIV2L , one component of the Ski complex, acts as an RNA helicase with a role in exosome recruitment or activation. It is involved in the degradation of RNAs by the exosome and may have a role in autophagy [PMID:11719186].