验证数据展示
产品信息
13238-1-PBS targets SLC22A4 in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 | SLC22A4 fusion protein Ag3974 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | solute carrier family 22 (organic cation/ergothioneine transporter), member 4 |
| 别名 | |
| 计算分子量 | 551 aa, 62 kDa |
| 观测分子量 | 62-70 kDa |
| GenBank蛋白编号 | BC028313 |
| 基因名称 | SLC22A4 |
| Gene ID (NCBI) | 6583 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H015 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC22A4 (solute carrier family 22 member 4), also known as OCTN1. It is expected to be located in cell membrane and mitochondrion membrane. It is strongly expressed in kidney, trachea, bone marrow and fetal liver and in several human cancer cell lines, but not in adult liver (PMID: 9426230). The protein functions as a Na+-dependent and pH-dependent high affinity microbial symporter of potent food-derived antioxidant ergothioeine (PubMed:15795384), which transports one sodium ion with one ergothioeine molecule. The calculated molecular weight of SLC22A4 is 62 kDa, the band of 70 kDa is glycosylated (PMID:26724204).