验证数据展示
Planning an IHC experiment? We recommend our IHCeasy SLC22A7 Ready-To-Use IHC Kit. SLC22A7 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67479-1-Ig
产品信息
CL594-67479 targets SLC22A7 in applications and shows reactivity with human samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human |
| 免疫原 | SLC22A7 fusion protein Ag25234 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | solute carrier family 22 (organic anion transporter), member 7 |
| 别名 | OAT2, NLT, hOAT2, 3D3C3 |
| 计算分子量 | 60 kDa |
| 观测分子量 | 60 kDa |
| GenBank蛋白编号 | BC033805 |
| 基因名称 | SLC22A7 |
| Gene ID (NCBI) | 10864 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9Y694 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Organic anion transporter (OAT)2 (SLC22A7) belongs to the solute carrier group of membrane transport proteins that mediate cellular uptake of numerous organic ions including xenobiotics and endogenous substrates (PMID: 9529348, 20190416). SLC22A7 was originally identified as a novel liver-specific transporter because of its predominant mRNA expression in the rat liver (PMID: 15900017, 25904762). Human SLC22A7 exhibits a robust transport function for a wide array of naturally occurring nucleobases, nucleosides, and nucleotides with a particular role for cGMP (PMID: 18216183).