CoraLite® Plus 488-conjugated SLC25A22 Polyclonal antibody
SLC25A22 Polyclonal Antibody for IF-P
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
验证数据展示
经过测试的应用
Positive IF-P detected in | mouse brain tissue |
For other applications, we recommend the unconjugated version of this antibody, 25402-1-AP
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-25402 targets SLC25A22 in IF-P applications and shows reactivity with human, mouse, rat samples.
Tested Applications | IF-P Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | SLC25A22 fusion protein Ag19958 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
Synonyms | FLJ13044, GC 1, GC1, Glutamate/H(+) symporter 1, SLC25A22 |
Calculated Molecular Weight | 323 aa, 34 kDa |
Observed Molecular Weight | 30-34 kDa |
GenBank Accession Number | BC023545 |
Gene Symbol | SLC25A22 |
Gene ID (NCBI) | 79751 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9H936 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLC25A22 encodes a mitochondrial glutamate/H+ symporter with highly expression in brain, especially in astrocytes, where it controls glutamate uptake. The mutations of SLC25A22 are associated with the early/infantile epileptic encephalopathies. It has been shown that SLC25A22 plays a key role in promoting proliferation and migration in cancer, such as human colorectal cancer (CRC) and Gallbladder cancer (GBC). And there is a result that the expression of SLC25A22 in GBC was significantly higher than that in adjacent tissues. 25402-1-AP antibody is specific to SLC25A22.(PMID: 30814911, 25033742, 24596948)
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 SLC25A22 antibody CL488-25402 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |