验证数据展示
产品信息
82895-2-PBS targets SLC30A1 in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, FC (Intra), Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | SLC30A1 fusion protein Ag18567 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | solute carrier family 30 (zinc transporter), member 1 |
Synonyms | ZnT-1, ZNT1, Zinc transporter 1, 230152E10 |
Calculated Molecular Weight | 507 aa, 55 kDa |
Observed Molecular Weight | 63~75 kDa |
GenBank Accession Number | BC121015 |
Gene Symbol | SLC30A1 |
Gene ID (NCBI) | 7779 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9Y6M5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Zinc transporter 1 (ZNT1), also known as SLC30A1, is the only zinc transporter predominantly located on the plasma membrane, where it plays a pivotal role exporting cytosolic zinc to the extracellular space. SLC30A1 expression is posttranslationally regulated by cellular zinc status and can be N-glycosylated on Asn299 in the extracellular loop between transmembrane domains (PMID: 15451416, 18936201). Western analysis detected a higher band at ~63 kDa than the expected molecular mass, which could be attributed to the properties of the cytosolic histidine-rich loop (PMID: 31471319).