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SLCO1B3/OATP1B3 Polyclonal antibody, PBS Only

SLCO1B3/OATP1B3 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 22815-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 22815-1-AP (same clone as 22815-1-PBS)

    WB analysis using 22815-1-AP (same clone as 22815-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22815-1-AP (SLCO1B3/OATP1B3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22815-1-PBS in a different storage buffer formulation.

产品信息

22815-1-PBS targets SLCO1B3/OATP1B3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen SLCO1B3/OATP1B3 fusion protein Ag18940 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier organic anion transporter family, member 1B3
Synonyms
Calculated Molecular Weight 702 aa, 77 kDa
Observed Molecular Weight 70-75 kDa
GenBank Accession NumberBC105597
Gene Symbol SLCO1B3
Gene ID (NCBI) 28234
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NPD5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).