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Species Reactivity
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验证数据展示

  • IF Staining of MDCK using 66851-2-Ig (same clone as 66851-2-PBS)

    IF Staining of MDCK using 66851-2-Ig (same clone as 66851-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MDCK cells using SMO antibody (66851-2-Ig, Clone: 2A11A10 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L), ARL13B antibody (17711-1-AP, red). This data was developed using the same antibody clone with 66851-2-PBS in a different storage buffer formulation.

SMO Monoclonal antibody, PBS Only

SMO Monoclonal Antibody for IF/ICC, Indirect ELISA
Cat No. 66851-2-PBS

产品说明书

CloneNo. 2A11A10

宿主/亚型

Mouse / IgG1

种属反应性

Human, Canine

应用

IF/ICC, Indirect ELISA

别名

Gx, Protein Gx, SMO, SMOH, Smoothened homolog

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy SMO Ready-To-Use IHC Kit. SMO primary antibody included.

产品信息

66851-2-PBS targets SMO in IF/ICC, Indirect ELISA applications and shows reactivity with Human, Canine samples.

经测试应用 IF/ICC, Indirect ELISA Application Description
经测试反应性 Human, Canine
免疫原 SMO fusion protein Ag25861 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 smoothened homolog (Drosophila)
别名 Gx, Protein Gx, SMO, SMOH, Smoothened homolog
计算分子量 787 aa, 86 kDa
GenBank蛋白编号BC009989
基因名称 SMO
Gene ID (NCBI) 6608
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99835
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Smoothened (SMO) is a G protein-coupled receptor that is a component of the hedgehog (Hh) signaling pathway and is conserved from flies to humans. The Hh pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. Expressed on the primary cilium, SMO interacts with the patched protein, a receptor for Hh proteins.