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SMO Monoclonal antibody, PBS Only

SMO Monoclonal Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Canine

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A11A10

Cat no : 66851-2-PBS

Print datasheet

Synonyms

Gx, Protein Gx, SMO, SMOH, Smoothened homolog

验证数据展示

  • IF Staining of MDCK using 66851-2-Ig (same clone as 66851-2-PBS)

    IF Staining of MDCK using 66851-2-Ig (same clone as 66851-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MDCK cells using SMO antibody (66851-2-Ig, Clone: 2A11A10 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L), ARL13B antibody (17711-1-AP, red). This data was developed using the same antibody clone with 66851-2-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy SMO Ready-To-Use IHC Kit. SMO primary antibody included.

产品信息

66851-2-PBS targets SMO in IF/ICC, Indirect ELISA applications and shows reactivity with Human, Canine samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity Human, Canine
Immunogen SMO fusion protein Ag25861 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name smoothened homolog (Drosophila)
Synonyms Gx, Protein Gx, SMO, SMOH, Smoothened homolog
Calculated Molecular Weight 787 aa, 86 kDa
GenBank Accession NumberBC009989
Gene Symbol SMO
Gene ID (NCBI) 6608
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ99835
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Smoothened (SMO) is a G protein-coupled receptor that is a component of the hedgehog (Hh) signaling pathway and is conserved from flies to humans. The Hh pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. Expressed on the primary cilium, SMO interacts with the patched protein, a receptor for Hh proteins.