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  • Featured Product
  • KD/KO Validated

SND1 Monoclonal antibody, PBS Only

SND1 Monoclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A6A4

Cat no : 60265-1-PBS

Print datasheet

Synonyms

100 kDa coactivator, EBNA2 coactivator p100, p100, p100 co activator, SND1, TDRD11

验证数据展示

  • WB analysis of Jurkat using 60265-1-Ig (same clone as 60265-1-PBS)

    WB analysis of Jurkat using 60265-1-Ig (same clone as 60265-1-PBS)

    WB result of SND1 antibody (60265-1-Ig, 1:60,000) with si-Control and si-SND1 transfected Jurkat cells. This data was developed using the same antibody clone with 60265-1-PBS in a different storage buffer formulation.

  • WB analysis using 60265-1-Ig (same clone as 60265-1-PBS)

    WB analysis using 60265-1-Ig (same clone as 60265-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60265-1-Ig (SND1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60265-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 60265-1-Ig (same clone as 60265-1-PBS)

    IF Staining of HepG2 using 60265-1-Ig (same clone as 60265-1-PBS)

    Immunofluorescent analysis of HepG2 cells using 60265-1-Ig(SND1 antibody) at dilution of 1:50 and and Rhodamine-labeled goat anti-mouse IgG (red). This data was developed using the same antibody clone with 60265-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 60265-1-Ig (same clone as 60265-1-PBS)

    IP experiment of HeLa using 60265-1-Ig (same clone as 60265-1-PBS)

    IP result of anti-SND1 (IP:60265-1-Ig, 5ug; Detection:60265-1-Ig 1:500) with HeLa cells lysate 1400ug. This data was developed using the same antibody clone with 60265-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas using 60265-1-Ig (same clone as 60265-1-PBS)

    IHC staining of human pancreas using 60265-1-Ig (same clone as 60265-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 60265-1-Ig (SND1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60265-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SND1 antibody included
  • IHC staining of human colon cancer using 60265-1-Ig (same clone as 60265-1-PBS)

    IHC staining of human colon cancer using 60265-1-Ig (same clone as 60265-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 60265-1-Ig (SND1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60265-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SND1 antibody included
Planning an IHC experiment? We recommend our IHCeasy SND1 Ready-To-Use IHC Kit. SND1 primary antibody included.

产品信息

60265-1-PBS targets SND1 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SND1 fusion protein Ag1200 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name staphylococcal nuclease and tudor domain containing 1
Synonyms 100 kDa coactivator, EBNA2 coactivator p100, p100, p100 co activator, SND1, TDRD11
Calculated Molecular Weight 101 kDa
Observed Molecular Weight 101 kDa
GenBank Accession NumberBC017180
Gene Symbol SND1
Gene ID (NCBI) 27044
RRIDAB_2881386
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ7KZF4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Staphylococcal nuclease domain-containing 1 (SND1), is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5, 6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC), and takes part in the functions of miRNA, regulates transcription through transcriptional coactivation, RNA interference, RNA splicing, and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer, can promote HCC angiogenesis in xenograft model through induction of angiogenic factors.