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验证数据展示

  • IF Staining of HepG2 using CL594-60265

    IF Staining of HepG2 using CL594-60265

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CoraLite®594-conjugated SND1 antibody (CL594-60265, Clone: 1A6A4 ) at dilution of 1:100.

  • Featured Product
  • KD/KO验证

CoraLite®594-conjugated SND1 Monoclonal antibody

SND1 Monoclonal Antibody for IF/ICC
Cat No. CL594-60265

产品说明书

CloneNo. 1A6A4

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IF/ICC

别名

100 kDa coactivator, EBNA2 coactivator p100, p100, p100 co activator, SND1, TDRD11

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHepG2 cells
Planning an IHC experiment? We recommend our IHCeasy SND1 Ready-To-Use IHC Kit. SND1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 60265-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-60265 targets SND1 in IF/ICC applications and shows reactivity with human samples.

经测试应用 IF/ICC Application Description
经测试反应性 human
免疫原 SND1 fusion protein Ag1200 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 staphylococcal nuclease and tudor domain containing 1
别名 100 kDa coactivator, EBNA2 coactivator p100, p100, p100 co activator, SND1, TDRD11
计算分子量 101 kDa
观测分子量 101 kDa
GenBank蛋白编号BC017180
基因名称 SND1
Gene ID (NCBI) 27044
RRIDAB_2919906
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ7KZF4
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Staphylococcal nuclease domain-containing 1 (SND1), is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5, 6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC), and takes part in the functions of miRNA, regulates transcription through transcriptional coactivation, RNA interference, RNA splicing, and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer, can promote HCC angiogenesis in xenograft model through induction of angiogenic factors.

实验方案

Product Specific Protocols
IF protocol for CL594 SND1 antibody CL594-60265Download protocol
Standard Protocols
Click here to view our Standard Protocols