验证数据展示
产品信息
67280-1-PBS targets SNRPN/SNRPB in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | SNRPN/SNRPB fusion protein Ag14030 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | small nuclear ribonucleoprotein polypeptide N |
别名 | SNRPN, SMN, Sm-D, Small nuclear ribonucleoprotein-associated protein N, SM D |
计算分子量 | 240 aa, 25 kDa |
观测分子量 | 27-29 kDa |
GenBank蛋白编号 | BC000611 |
基因名称 | SNRPN |
Gene ID (NCBI) | 6638 |
RRID | AB_2882548 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P63162 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SNRPN, or SNURF-SNRPN, is a bicistronic imprinted gene that encodes 2 polypeptides, the SmN splicing factor, which is involved in RNA processing, and the SNRPN upstream reading frame (SNURF) polypeptide.The SNRPN gene is transcribed exclusively from the paternally inherited chromosome and shows highest expression in brain and heart. SNRPN may play a role in etiology of Prader-Willi syndrome. This antibody recognizes SNRPN and SNRPB due to high amino acid sequence homology.