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SPIN1 Monoclonal antibody, PBS Only

SPIN1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G8C5

Cat no : 68615-1-PBS

Print datasheet

Synonyms

OCR, Ovarian cancer related protein, SPIN, SPIN1, spindlin 1

验证数据展示

  • WB analysis using 68615-1-Ig (same clone as 68615-1-PBS)

    WB analysis using 68615-1-Ig (same clone as 68615-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68615-1-Ig (SPIN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68615-1-PBS in a different storage buffer formulation.

  • WB analysis using 68615-1-Ig (same clone as 68615-1-PBS)

    WB analysis using 68615-1-Ig (same clone as 68615-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68615-1-Ig (SPIN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68615-1-PBS in a different storage buffer formulation.

产品信息

68615-1-PBS targets SPIN1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, rabbit
Immunogen SPIN1 fusion protein Ag33686 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name spindlin 1
Synonyms OCR, Ovarian cancer related protein, SPIN, SPIN1, spindlin 1
Calculated Molecular Weight 262 aa, 30 kDa
Observed Molecular Weight 30 kDa
GenBank Accession NumberBC013571
Gene Symbol SPIN1
Gene ID (NCBI) 10927
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y657
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SPIN1 (Spindlin 1) is a histone methylation reader, which recognizes trimethylated histone H3 lysine 4 through the protein-protein interaction. SPIN1 was initially found in ovarian cancer via searching ovarian cancer-related genes . It is overexpressed in ovarian cancer tissue, which exhibits a high homology to mouse Spin (Spindlin) gene. Signaling pathways responsible for SPIN1 functions include PI3K/Akt, Wnt and RET that are highly relevant to tumorigenesis.(PMID: 34492335, PMID: 31790762)