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验证数据展示

  • WB analysis of LNCaP using 66859-1-Ig (same clone as 66859-1-PBS)

    WB analysis of LNCaP using 66859-1-Ig (same clone as 66859-1-PBS)

    LNCaP cells were subjected to SDS PAGE followed by western blot with 66859-1-Ig (SPON2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66859-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 66859-1-Ig (same clone as 66859-1-PBS)

    IHC staining of human prostate cancer using 66859-1-Ig (same clone as 66859-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66859-1-Ig (SPON2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66859-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 66859-1-Ig (same clone as 66859-1-PBS)

    IHC staining of human prostate cancer using 66859-1-Ig (same clone as 66859-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66859-1-Ig (SPON2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66859-1-PBS in a different storage buffer formulation.

SPON2 Monoclonal antibody, PBS Only

SPON2 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66859-1-PBS

产品说明书

CloneNo. 1H4B11

宿主/亚型

Mouse / IgG2a

种属反应性

Human

应用

WB, IHC, Indirect ELISA

别名

DIL 1, DIL1, M spondin, Mindin, SPON2, Spondin 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66859-1-PBS targets SPON2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 SPON2 fusion protein Ag14337 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 spondin 2, extracellular matrix protein
别名 DIL 1, DIL1, M spondin, Mindin, SPON2, Spondin 2
计算分子量 331 aa, 36 kDa
观测分子量 38 kDa
GenBank蛋白编号BC002707
基因名称 SPON2
Gene ID (NCBI) 10417
RRIDAB_2882198
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9BUD6
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SPON2 (Spondin 2), also known as Mindin, is a member of the F-spondin family of secreted extracellular matrix proteins. This protein has been implicated in axon guidance, immune response and adhesion. SPON2 is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (PMID: 14691481). It also functions as an integrin ligand for inflammatory cell recruitment and T-cell priming (PMID: 19153605). Besides, SPON2 has been reported as a prognostic biomarker for ovarian and prostate cancer (PMID: 17490732; 22615945; 23665271).