验证数据展示
产品信息
67978-1-PBS targets SPTBN1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit, pig samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, rat, rabbit, pig |
免疫原 | SPTBN1 fusion protein Ag31713 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | spectrin, beta, non-erythrocytic 1 |
别名 | Beta II spectrin, betaSpII, ELF, Fodrin beta chain, Spectrin beta chain, brain 1, SPTB2, SPTBN1 |
计算分子量 | 2364 aa, 275 kDa |
观测分子量 | 250-275 kDa |
GenBank蛋白编号 | BC137282 |
基因名称 | SPTBN1 |
Gene ID (NCBI) | 6711 |
RRID | AB_2918727 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q01082 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.