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SPTBN1 Monoclonal antibody, PBS Only

SPTBN1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, rabbit, pig

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1E1D1

Cat no : 67978-1-PBS

Print datasheet

Synonyms

Beta II spectrin, betaSpII, ELF, Fodrin beta chain, Spectrin beta chain, brain 1, SPTB2, SPTBN1

验证数据展示

  • WB analysis using 67978-1-Ig (same clone as 67978-1-PBS)

    WB analysis using 67978-1-Ig (same clone as 67978-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67978-1-Ig (SPTBN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 67978-1-Ig (same clone as 67978-1-PBS)

    IHC staining of human liver cancer using 67978-1-Ig (same clone as 67978-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67978-1-Ig (SPTBN1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SPTBN1 antibody included
Planning an IHC experiment? We recommend our IHCeasy SPTBN1 Ready-To-Use IHC Kit. SPTBN1 primary antibody included.

产品信息

67978-1-PBS targets SPTBN1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit, pig samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, mouse, rat, rabbit, pig
Immunogen SPTBN1 fusion protein Ag31713 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name spectrin, beta, non-erythrocytic 1
Synonyms Beta II spectrin, betaSpII, ELF, Fodrin beta chain, Spectrin beta chain, brain 1, SPTB2, SPTBN1
Calculated Molecular Weight 2364 aa, 275 kDa
Observed Molecular Weight250-275 kDa
GenBank Accession NumberBC137282
Gene Symbol SPTBN1
Gene ID (NCBI) 6711
RRIDAB_2918727
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ01082
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.