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验证数据展示

  • WB analysis of pig lung using 66266-1-Ig (same clone as 66266-1-PBS)

    WB analysis of pig lung using 66266-1-Ig (same clone as 66266-1-PBS)

    pig lung tissue were subjected to SDS PAGE followed by western blot with 66266-1-Ig (SRPX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66266-1-Ig (SRPX2 Antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66266-1-Ig (SRPX2 Antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 66266-1-Ig (same clone as 66266-1-PBS)

    IF Staining of A549 using 66266-1-Ig (same clone as 66266-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using SRPX2 antibody (66266-1-Ig, Clone: 2A1D7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SRPX2 Monoclonal antibody, PBS Only

SRPX2 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66266-1-PBS

产品说明书

CloneNo. 2A1D7

宿主/亚型

Mouse / IgG2b

种属反应性

human, pig, mouse

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66266-1-PBS targets SRPX2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, pig, mouse samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, pig, mouse
免疫原 SRPX2 fusion protein Ag8084 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 sushi-repeat-containing protein, X-linked 2
别名 BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2
计算分子量 465 aa, 53 kDa
观测分子量 53 kDa
GenBank蛋白编号BC020733
基因名称 SRPX2
Gene ID (NCBI) 27286
RRIDAB_2721268
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO60687
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SRPX2 (sushi-repeat-containing protein, X-linked 2) is a secreted protein expressed in neurons of the human adult brain, including the rolandic area (PMID: 20874700). Firstly described as sushi-repeat protein up-regulated in leukemia (SPRUL) in leukemia cells with dysregulated expression at the transcriptional level, SRPX2 has been recently shown as a multifunctional protein. SRPX2 is a ligand for uPAR, the urokinase-type plasminogen activator (uPA) receptor (PMID: 18718938). It is involved in seizure disorders, angiogenesis and cellular adhesion (PMID: 22242148; 19667118; 16497722). The involvement of SRPX2 in disorders of language cortex suggests it has an important role in the perisylvian region critical for language and cognitive development (PMID: 16497722).