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  • Featured Product
  • KD/KO Validated

SRPX2 Monoclonal antibody, PBS Only

SRPX2 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, pig, mouse

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A1D7

Cat no : 66266-1-PBS

Print datasheet

Synonyms

BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2

验证数据展示

  • WB analysis of pig lung using 66266-1-Ig (same clone as 66266-1-PBS)

    WB analysis of pig lung using 66266-1-Ig (same clone as 66266-1-PBS)

    pig lung tissue were subjected to SDS PAGE followed by western blot with 66266-1-Ig (SRPX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66266-1-Ig (SRPX2 Antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    IHC staining of mouse brain using 66266-1-Ig (same clone as 66266-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66266-1-Ig (SRPX2 Antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 66266-1-Ig (same clone as 66266-1-PBS)

    IF Staining of A549 using 66266-1-Ig (same clone as 66266-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using SRPX2 antibody (66266-1-Ig, Clone: 2A1D7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66266-1-PBS in a different storage buffer formulation.

产品信息

66266-1-PBS targets SRPX2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, pig, mouse samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, pig, mouse
Immunogen SRPX2 fusion protein Ag8084 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name sushi-repeat-containing protein, X-linked 2
Synonyms BPP, CBPS, PMGX, RESDX, SRPUL, SRPX2
Calculated Molecular Weight 465 aa, 53 kDa
Observed Molecular Weight 53 kDa
GenBank Accession NumberBC020733
Gene Symbol SRPX2
Gene ID (NCBI) 27286
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO60687
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SRPX2 (sushi-repeat-containing protein, X-linked 2) is a secreted protein expressed in neurons of the human adult brain, including the rolandic area (PMID: 20874700). Firstly described as sushi-repeat protein up-regulated in leukemia (SPRUL) in leukemia cells with dysregulated expression at the transcriptional level, SRPX2 has been recently shown as a multifunctional protein. SRPX2 is a ligand for uPAR, the urokinase-type plasminogen activator (uPA) receptor (PMID: 18718938). It is involved in seizure disorders, angiogenesis and cellular adhesion (PMID: 22242148; 19667118; 16497722). The involvement of SRPX2 in disorders of language cortex suggests it has an important role in the perisylvian region critical for language and cognitive development (PMID: 16497722).