IL-1RL1/ST2 Monoclonal antibody, PBS Only

IL-1RL1/ST2 Monoclonal Antibody for WB, ELISA
Cat No. 60112-1-PBS

产品说明书

CloneNo. 7A2A7

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig

应用

WB, ELISA

IL1RL1, IL-1RL1, FIT 1, EC:3.2.2.6, DER4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy IL1RL1/ST2 Ready-To-Use IHC Kit. IL1RL1/ST2 primary antibody included.

产品信息

60112-1-PBS targets IL-1RL1/ST2 in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原 IL-1RL1/ST2 fusion protein Ag2555 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 1 receptor-like 1
别名 IL1RL1, IL-1RL1, FIT 1, EC:3.2.2.6, DER4
计算分子量 63 kDa, 37 kDa, 30 kDa
观测分子量 63 kDa
GenBank蛋白编号BC030975
基因名称 IL1RL1
Gene ID (NCBI) 9173
RRIDAB_2264785
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ01638
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ST2, also known as IL1RL1, is a member of the IL-1 superfamily and serves as the receptor for IL-33. It plays a major role in immune and inflammatory responses. ST2 is expressed by various types of immune cells including Th2 cells, mast cells, type 2 innate lymphoid cells, eosinophils, basophils, NK cells, and non-immune cells, including cardiomyocytes. Two forms of ST2 exist: a membrane-bound form and a soluble form (sST2). The membrane-bound form activates the MyD88/NF-κB signaling pathway to enhance mast cell, Th2, regulatory T cell (Treg), and innate lymphoid cell type 2 functions. sST2 acts as a decoy receptor. (PMID: 27055914; 23999434; 28484466)

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