ST6GALNAC4 Polyclonal antibody, PBS Only

ST6GALNAC4 Polyclonal Antibody for IP, Indirect ELISA
Cat No. 15654-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IP, Indirect ELISA

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

15654-1-PBS targets ST6GALNAC4 in IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 ST6GALNAC4 fusion protein Ag7995 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
别名
计算分子量 34 kDa
观测分子量35 kDa
GenBank蛋白编号BC036705
基因名称 ST6GALNAC4
Gene ID (NCBI) 27090
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H4F1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (also known as ST6GALNAC4) is a member of the sialyltransferases, which catalyzes the transfer of sialic acid from cytidine monosphosphate (CMP)-sialic acid to galactose-containing substrates. ST6GALNAC4 may be induced abnormal TGFBR2 glycosylation, resulting in the higher protein levels of TGFBR2 and TGF pathway increased activation (PMID: 37381011, 37034303). ST6GALNAC4 was reported to influence patient prognosis though subverting immunosurveillance in Chronic lymphocytic leukemia.

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