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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 80149-1-RR (same clone as 80149-1-PBS)

    WB analysis using 80149-1-RR (same clone as 80149-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 80149-1-RR (STAT3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80149-1-PBS in a different storage buffer formulation.

  • WB analysis using 80149-1-RR (same clone as 80149-1-PBS)

    WB analysis using 80149-1-RR (same clone as 80149-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 80149-1-RR (STAT3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80149-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 80149-1-RR (same clone as 80149-1-PBS)

    WB analysis of HeLa using 80149-1-RR (same clone as 80149-1-PBS)

    WB result of STAT3 antibody (80149-1-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-STAT3 transfected HeLa cells. This data was developed using the same antibody clone with 80149-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

STAT3 Recombinant antibody, PBS Only

STAT3 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 80149-1-PBS

产品说明书

CloneNo. 3H1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

STAT 3, HIES, APRF, Acute-phase response factor, 3H1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy STAT3 Ready-To-Use IHC Kit. STAT3 primary antibody included.

产品信息

80149-1-PBS targets STAT3 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 signal transducer and activator of transcription 3 (acute-phase response factor)
别名 STAT 3, HIES, APRF, Acute-phase response factor, 3H1
计算分子量 770 aa, 88 kDa
观测分子量88 kDa
GenBank蛋白编号BC000627
基因名称 STAT3
Gene ID (NCBI) 6774
RRIDAB_2918869
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP40763
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3, synonyms: APRF, FLJ20882, MGC16063) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3.