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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 84822-4-RR (same clone as 84822-4-PBS)

    WB analysis using 84822-4-RR (same clone as 84822-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84822-4-RR (STAU1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84822-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84822-4-RR

    Affinity and Kinetic Characterization of 84822-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84822-4-RR against Human STAU1 were performed. The affinity constant is below 1 pM.

STAU1 Recombinant antibody, PBS Only

STAU1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84822-4-PBS

产品说明书

CloneNo. 242179D12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

STAU, Double-stranded RNA-binding protein Staufen homolog 1, 242179D12

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy STAU1 Ready-To-Use IHC Kit. STAU1 primary antibody included.

产品信息

84822-4-PBS targets STAU1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 STAU1 fusion protein Ag5464 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 staufen, RNA binding protein, homolog 1 (Drosophila)
别名 STAU, Double-stranded RNA-binding protein Staufen homolog 1, 242179D12
计算分子量 63 kDa
观测分子量55-65 kDa
GenBank蛋白编号BC050432
基因名称 STAU1
Gene ID (NCBI) 6780
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO95793
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs) [PMID:21307942]. STAU1 can binds to stem structures and protect Dvl2 mRNA from degradation by associating with the secondary structure in the U1 region which is located at 5′ position of second U stretch in the U2 region [PMID:17510634]. It has a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.