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验证数据展示

  • WB analysis using 84822-4-RR

    WB analysis using 84822-4-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 84822-4-RR (STAU1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 84822-4-RR

    Affinity and Kinetic Characterization of 84822-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84822-4-RR against Human STAU1 were performed. The affinity constant is below 1 pM.

STAU1 Recombinant antibody

STAU1 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 84822-4-RR

产品说明书

CloneNo. 242179D12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

STAU, Double-stranded RNA-binding protein Staufen homolog 1, 242179D12

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inJurkat cells, K-562 cells, HepG2 cells
Planning an IHC experiment? We recommend our IHCeasy STAU1 Ready-To-Use IHC Kit. STAU1 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84822-4-RR targets STAU1 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 STAU1 fusion protein Ag5464 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 staufen, RNA binding protein, homolog 1 (Drosophila)
别名 STAU, Double-stranded RNA-binding protein Staufen homolog 1, 242179D12
计算分子量 63 kDa
观测分子量55-65 kDa
GenBank蛋白编号BC050432
基因名称 STAU1
Gene ID (NCBI) 6780
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO95793
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs) [PMID:21307942]. STAU1 can binds to stem structures and protect Dvl2 mRNA from degradation by associating with the secondary structure in the U1 region which is located at 5′ position of second U stretch in the U2 region [PMID:17510634]. It has a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.

实验方案

Product Specific Protocols
WB protocol for STAU1 antibody 84822-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols