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验证数据展示

  • IHC staining of human lymphoma using 25471-1-AP (same clone as 25471-1-PBS)

    IHC staining of human lymphoma using 25471-1-AP (same clone as 25471-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 25471-1-AP (STK10 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25471-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 25471-1-AP (same clone as 25471-1-PBS)

    IHC staining of human lymphoma using 25471-1-AP (same clone as 25471-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 25471-1-AP (STK10 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25471-1-PBS in a different storage buffer formulation.

  • WB analysis of SKOV-3 using 25471-1-AP (same clone as 25471-1-PBS)

    WB analysis of SKOV-3 using 25471-1-AP (same clone as 25471-1-PBS)

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with 25471-1-AP (STK10 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25471-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

STK10 Polyclonal antibody, PBS Only

STK10 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 25471-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

serine/threonine kinase 10, PRO2729, Lymphocyte-oriented kinase, Lymphocyte oriented kinase, LOK

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

25471-1-PBS targets STK10 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 STK10 fusion protein Ag22169 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 serine/threonine kinase 10
别名 serine/threonine kinase 10, PRO2729, Lymphocyte-oriented kinase, Lymphocyte oriented kinase, LOK
计算分子量 968 aa, 112 kDa
观测分子量 130 kDa
GenBank蛋白编号BC070077
基因名称 STK10
Gene ID (NCBI) 6793
RRIDAB_2880096
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO94804
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Lymphocyte-oriented kinase deficiency encoded by the serine/threonine kinase 10 (STK10) gene correlates with the intracellular adhesion molecule 1 (ICAM-1)/lymphocyte function associated antigen 1 (LFA-1) complex in aspirin hypersensitivity(PMID:21905501). STK 10 is also named as LOK and expressed as a 130-kDa protein, which was detected predominantly in lymphoid organs such as spleen, thymus, and bone marrow, in contrast to other mammalian members of the STE20 family(PMID:9278426).