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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 27556-1-AP (same clone as 27556-1-PBS)

    WB analysis using 27556-1-AP (same clone as 27556-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27556-1-AP (SUN2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27556-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 27556-1-AP (same clone as 27556-1-PBS)

    WB analysis of HeLa using 27556-1-AP (same clone as 27556-1-PBS)

    WB result of SUN2 antibody (27556-1-AP; 1:5000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SUN2 transfected HeLa cells. This data was developed using the same antibody clone with 27556-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 27556-1-AP (same clone as 27556-1-PBS)

    IF Staining of HeLa using 27556-1-AP (same clone as 27556-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using SUN2 antibody (27556-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 27556-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

SUN2 Polyclonal antibody, PBS Only

SUN2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 27556-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

UNC84B, SUN domain-containing protein 2, Sad1/unc-84 protein-like 2, Rab5-interacting protein, Protein unc-84 homolog B

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

27556-1-PBS targets SUN2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen SUN2 fusion protein Ag16077 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name unc-84 homolog B (C. elegans)
Synonyms UNC84B, SUN domain-containing protein 2, Sad1/unc-84 protein-like 2, Rab5-interacting protein, Protein unc-84 homolog B
Calculated Molecular Weight 717 aa, 80 kDa
Observed Molecular Weight 80-85 kDa
GenBank Accession NumberBC111717
Gene Symbol SUN2
Gene ID (NCBI) 25777
RRIDAB_2880906
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UH99
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SUN2, also known as UNC84B, RAB5IP, belongs to the SUN (Sad1 and UNC84) protein family, which is a group of conserved proteins in eukaryotes. SUN2 is a key component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, which connects the nuclear lamina to the cytoskeleton. This connection is crucial for the transmission of mechanical forces across the nuclear envelope and for nuclear movement and positioning (PMID: 18396275).