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Host
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0
Species Reactivity
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0
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验证数据展示

  • WB analysis using 12359-1-AP (same clone as 12359-1-PBS)

    WB analysis using 12359-1-AP (same clone as 12359-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12359-1-AP (SYTL2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12359-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12359-1-AP (SYTL2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12359-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12359-1-AP (SYTL2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12359-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

SYTL2 Polyclonal antibody, PBS Only

SYTL2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12359-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

12359-1-PBS targets SYTL2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SYTL2 fusion protein Ag3023 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 synaptotagmin-like 2
别名
计算分子量 934 aa, 105 kDa
观测分子量39 kDa, 100-105 kDa
GenBank蛋白编号BC015540
基因名称 SYTL2
Gene ID (NCBI) 54843
RRIDAB_11182492
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9HCH5
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Synaptotagmin-like 2 (SYTL2) is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. SYTL2 contains an N-terminal Slp homology domain (SHD), Rab-binding region, and C-terminal tandem C2 domains, C2A and C2B (PMID: 11327731). It interacts with RAB27A and plays a role in promoting docking of RAB27-bound organelles to the plasma membrane (PMID: 17052176). Alternative splicing of SYTL2 gene results in multiple transcript variants encoding distinct isoforms with calculated molecular weights ranging from 39 kDa to 142 kDa.