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  • Featured Product
  • KD/KO Validated

SYTL2 Polyclonal antibody, PBS Only

SYTL2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12359-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 12359-1-AP (same clone as 12359-1-PBS)

    WB analysis using 12359-1-AP (same clone as 12359-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12359-1-AP (SYTL2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12359-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12359-1-AP (SYTL2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12359-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    IHC staining of human breast cancer using 12359-1-AP (same clone as 12359-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12359-1-AP (SYTL2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12359-1-PBS in a different storage buffer formulation.

产品信息

12359-1-PBS targets SYTL2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen SYTL2 fusion protein Ag3023 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name synaptotagmin-like 2
Synonyms
Calculated Molecular Weight 934 aa, 105 kDa
Observed Molecular Weight39 kDa, 100-105 kDa
GenBank Accession NumberBC015540
Gene Symbol SYTL2
Gene ID (NCBI) 54843
RRIDAB_11182492
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9HCH5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Synaptotagmin-like 2 (SYTL2) is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. SYTL2 contains an N-terminal Slp homology domain (SHD), Rab-binding region, and C-terminal tandem C2 domains, C2A and C2B (PMID: 11327731). It interacts with RAB27A and plays a role in promoting docking of RAB27-bound organelles to the plasma membrane (PMID: 17052176). Alternative splicing of SYTL2 gene results in multiple transcript variants encoding distinct isoforms with calculated molecular weights ranging from 39 kDa to 142 kDa.