验证数据展示
产品信息
83564-5-PBS targets SYTL4 in WB, ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | SYTL4 fusion protein Ag2772 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | synaptotagmin-like 4 |
| Synonyms | synaptotagmin like 4, SLP4, Granuphilin, Exophilin-2, Exophilin 2 |
| Calculated Molecular Weight | 671 aa, 76 kDa |
| Observed Molecular Weight | 74-76 kDa |
| GenBank Accession Number | BC014913 |
| Gene Symbol | SYTL4 |
| Gene ID (NCBI) | 94121 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q96C24 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SYTL4, also known as SLP4 or granuphilin, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL4 is specifically expressed on dense-core granules in certain neuroendocrine cells and negatively controls dense-core vesicle exocytosis through specific interaction with Rab27A. (PMID: 16481396; 16473610)