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Synaptotagmin-1 Monoclonal antibody, PBS Only

Synaptotagmin-1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat, Pig, Rabbit, Chicken

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H1H2

Cat no : 68043-1-PBS

Print datasheet

Synonyms

DKFZp781D2042, P65, SVP65, Synaptotagmin 1, synaptotagmin I, Synaptotagmin-1, SYT, SYT1, SytI

验证数据展示

  • WB analysis using 68043-1-Ig (same clone as 68043-1-PBS)

    WB analysis using 68043-1-Ig (same clone as 68043-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68043-1-Ig (Synaptotagmin-1 antibody) at dilution of 1:50000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68043-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 68043-1-Ig (same clone as 68043-1-PBS)

    IHC staining of mouse brain using 68043-1-Ig (same clone as 68043-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68043-1-Ig (Synaptotagmin-1 antibody) at dilution of 1:5000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68043-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SYT1 antibody included
  • IHC staining of mouse brain using 68043-1-Ig (same clone as 68043-1-PBS)

    IHC staining of mouse brain using 68043-1-Ig (same clone as 68043-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 68043-1-Ig (Synaptotagmin-1 antibody) at dilution of 1:5000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68043-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SYT1 antibody included
Planning an IHC experiment? We recommend our IHCeasy SYT1 Ready-To-Use IHC Kit. SYT1 primary antibody included.

产品信息

68043-1-PBS targets Synaptotagmin-1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Pig, Rabbit, Chicken samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, Mouse, Rat, Pig, Rabbit, Chicken
Immunogen Synaptotagmin-1 fusion protein Ag6071 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name synaptotagmin I
Synonyms DKFZp781D2042, P65, SVP65, Synaptotagmin 1, synaptotagmin I, Synaptotagmin-1, SYT, SYT1, SytI
Calculated Molecular Weight 48 kDa
Observed Molecular Weight60-65 kDa
GenBank Accession NumberBC058917
Gene Symbol Synaptotagmin-1
Gene ID (NCBI) 6857
RRIDAB_2918785
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP21579
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). SYT1 (synaptotagmin I) was firstly identified as a 65-kDa protein with a wide distribution in neuronal and neurosecretory tissue (PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse (PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth (PMID: 15492212; 11078930; 10336114).