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验证数据展示

  • WB analysis of HaCaT using 27360-1-AP (same clone as 27360-1-PBS)

    WB analysis of HaCaT using 27360-1-AP (same clone as 27360-1-PBS)

    HaCaT cells were subjected to SDS PAGE followed by western blot with 27360-1-AP (TACSTD2 antibody) at dilution of 1:1200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 27360-1-AP (same clone as 27360-1-PBS)

    IHC staining of human breast cancer using 27360-1-AP (same clone as 27360-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27360-1-AP (TACSTD2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TACSTD2 antibody included
  • IHC staining of human breast cancer using 27360-1-AP (same clone as 27360-1-PBS)

    IHC staining of human breast cancer using 27360-1-AP (same clone as 27360-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27360-1-AP (TACSTD2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TACSTD2 antibody included
  • IF Staining of HaCaT using 27360-1-AP (same clone as 27360-1-PBS)

    IF Staining of HaCaT using 27360-1-AP (same clone as 27360-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HaCaT cells using TACSTD2/TROP2 antibody (27360-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

TACSTD2/TROP2 Polyclonal antibody, PBS Only

TACSTD2/TROP2 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 27360-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, ELISA

别名

TACSTD2, M1S1, GA733-1, GA733 1, GA733

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TACSTD2 Ready-To-Use IHC Kit. TACSTD2 primary antibody included.

产品信息

27360-1-PBS targets TACSTD2/TROP2 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
经测试反应性 human
免疫原 TACSTD2/TROP2 fusion protein Ag25769 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tumor-associated calcium signal transducer 2
别名 TACSTD2, M1S1, GA733-1, GA733 1, GA733
计算分子量 36 kDa
观测分子量45-55 kDa
GenBank蛋白编号BC009409
基因名称 TROP2
Gene ID (NCBI) 4070
RRIDAB_2918122
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP09758
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).