CoraLite® Plus 488-conjugated TACSTD2/TROP2 Monoclonal antibody
TACSTD2/TROP2 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
5A6B1
验证数据展示
经过测试的应用
| Positive IF/ICC detected in | HaCaT cells |
Planning an IHC experiment? We recommend our IHCeasy TACSTD2 Ready-To-Use IHC Kit. TACSTD2 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 68141-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-68141 targets TACSTD2/TROP2 in IF/ICC applications and shows reactivity with human samples.
| Tested Applications | IF/ICC Application Description |
| Tested Reactivity | human |
| Immunogen | TACSTD2/TROP2 fusion protein Ag25775 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | tumor-associated calcium signal transducer 2 |
| Synonyms | TACSTD2, GA733-1, GA733 1, GA733, EGP 1 |
| Calculated Molecular Weight | 36 kDa |
| Observed Molecular Weight | 40-50 kDa |
| GenBank Accession Number | BC009409 |
| Gene Symbol | TROP2 |
| Gene ID (NCBI) | 4070 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P09758 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 TACSTD2/TROP2 antibody CL488-68141 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |