验证数据展示
产品信息
67707-1-PBS targets TAK1 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Applications | WB, IHC, IF/ICC, ELISA Application Description |
Tested Reactivity | Human, Mouse, Rat |
Immunogen | TAK1 fusion protein Ag21286 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | mitogen-activated protein kinase kinase kinase 7 |
Synonyms | MAP3K7, TAK1, TGF beta activated kinase 1, TGF1a |
Calculated Molecular Weight | 579 aa, 64 kDa |
Observed Molecular Weight | 67-70 kDa |
GenBank Accession Number | BC017715 |
Gene Symbol | TAK1 |
Gene ID (NCBI) | 6885 |
RRID | AB_2882898 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | O43318 |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MAP3K7(Mitogen-activated protein kinase kinase kinase 7) is also named as TAK1 and belongs to the MAP kinase kinase kinase subfamily. It plays an important role in the cascades of cellular responses evoked by changes in the environment. It has been linked to interleukin-1 receptor and tumor necrosis factor receptor signaling (PMID: 16186825). It has 4 isoforms (53-55 kDa, 64-70 kDa and 75-80 kDa) produced by alternative splicing.