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验证数据展示

  • WB analysis using 67451-1-Ig (same clone as 67451-1-PBS)

    WB analysis using 67451-1-Ig (same clone as 67451-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67451-1-Ig (TAOK3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67451-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    IHC staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 67451-1-Ig (TAOK3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67451-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    IHC staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 67451-1-Ig (TAOK3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67451-1-PBS in a different storage buffer formulation.

  • IF Staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    IF Staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using TAOK3 antibody (67451-1-Ig, Clone: 1A5A9 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67451-1-PBS in a different storage buffer formulation.

  • IF Staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    IF Staining of human prostate cancer using 67451-1-Ig (same clone as 67451-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using TAOK3 antibody (67451-1-Ig, Clone: 1A5A9 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67451-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 67451-1-Ig (same clone as 67451-1-PBS)

    IHC staining of mouse kidney using 67451-1-Ig (same clone as 67451-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 67451-1-Ig (TAOK3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67451-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TAOK3 Monoclonal antibody, PBS Only

TAOK3 Monoclonal Antibody for WB, IHC, IF-P, ELISA
Cat No. 67451-1-PBS

产品说明书

CloneNo. 1A5A9

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse

应用

WB, IHC, IF-P, ELISA

别名

JIK, EC:2.7.11.1, DPK, Dendritic cell-derived protein kinase, Cutaneous T-cell lymphoma-associated antigen HD-CL-09

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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67451-1-Ig

产品信息

67451-1-PBS targets TAOK3 in WB, IHC, IF-P, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF-P, ELISA Application Description
经测试反应性 human, mouse
免疫原 TAOK3 fusion protein Ag29146 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 TAO kinase 3
别名 JIK, EC:2.7.11.1, DPK, Dendritic cell-derived protein kinase, Cutaneous T-cell lymphoma-associated antigen HD-CL-09
计算分子量 105 kDa
观测分子量 100-105 kDa
GenBank蛋白编号BC002756
基因名称 TAOK3
Gene ID (NCBI) 51347
RRIDAB_2882685
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9H2K8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TAOK3(Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated(PMID:20949042).