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验证数据展示

  • IF Staining of human prostate cancer using CL488-67451

    IF Staining of human prostate cancer using CL488-67451

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using CoraLite® Plus 488 TAOK3 antibody (CL488-67451, Clone: 1A5A9 ) at dilution of 1:200.

  • IF Staining of human prostate cancer using CL488-67451

    IF Staining of human prostate cancer using CL488-67451

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using CoraLite® Plus 488 TAOK3 antibody (CL488-67451, Clone: 1A5A9 ) at dilution of 1:200.

  • Featured Product
  • KD/KO验证

CoraLite® Plus 488-conjugated TAOK3 Monoclonal antibody

TAOK3 Monoclonal Antibody for IF-P
Cat No. CL488-67451

产品说明书

CloneNo. 1A5A9

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

IF-P

别名

DKFZp666H245, DPK, FLJ31808, hKFC A, JIK, JNK/SAPK inhibitory kinase, Jun kinase inhibitory kinase, KDS, Kinase from chicken homolog A, MAP3K18, TAO kinase 3, TAOK3

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inhuman prostate cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 67451-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67451 targets TAOK3 in IF-P applications and shows reactivity with Human samples.

经测试应用 IF-P Application Description
经测试反应性 Human
免疫原 TAOK3 fusion protein Ag29146 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 TAO kinase 3
别名 DKFZp666H245, DPK, FLJ31808, hKFC A, JIK, JNK/SAPK inhibitory kinase, Jun kinase inhibitory kinase, KDS, Kinase from chicken homolog A, MAP3K18, TAO kinase 3, TAOK3
计算分子量 105 kDa
观测分子量 100-105 kDa
GenBank蛋白编号BC002756
基因名称 TAOK3
Gene ID (NCBI) 51347
RRIDAB_2919477
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9H2K8
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TAOK3(Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated(PMID:20949042).

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TAOK3 antibody CL488-67451Download protocol
Standard Protocols
Click here to view our Standard Protocols