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CoraLite® Plus 488-conjugated TAOK3 Monoclonal antibody
TAOK3 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1A5A9
验证数据展示
经过测试的应用
Positive IF-P detected in | human prostate cancer tissue |
For other applications, we recommend the unconjugated version of this antibody, 67451-1-Ig
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-67451 targets TAOK3 in IF-P applications and shows reactivity with Human samples.
Tested Applications | IF-P Application Description |
Tested Reactivity | Human |
Immunogen | TAOK3 fusion protein Ag29146 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | TAO kinase 3 |
Synonyms | DKFZp666H245, DPK, FLJ31808, hKFC A, JIK, JNK/SAPK inhibitory kinase, Jun kinase inhibitory kinase, KDS, Kinase from chicken homolog A, MAP3K18, TAO kinase 3, TAOK3 |
Calculated Molecular Weight | 105 kDa |
Observed Molecular Weight | 100-105 kDa |
GenBank Accession Number | BC002756 |
Gene Symbol | TAOK3 |
Gene ID (NCBI) | 51347 |
RRID | AB_2919477 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9H2K8 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TAOK3(Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated(PMID:20949042).
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 TAOK3 antibody CL488-67451 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |