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TAX1BP1 Monoclonal antibody

TAX1BP1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1H2D10

Cat no : 60466-1-Ig

Print datasheet

Synonyms

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10

验证数据展示

  • WB analysis using 60466-1-Ig

    WB analysis using 60466-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 60466-1-Ig (TAX1BP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA549 cells, U2OS cells, HeLa cells, HepG2 cells, Jurkat cells, K-562 cells, HSC-T6 cells, NIH/3T3 cells, 4T1 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60466-1-Ig targets TAX1BP1 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Immunogen TAX1BP1 fusion protein Ag6279 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name Tax1 (human T-cell leukemia virus type I) binding protein 1
Synonyms TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10
Calculated Molecular Weight 91 kDa
Observed Molecular Weight68 kDa, 85 kDa
GenBank Accession NumberBC050358
Gene Symbol TAX1BP1
Gene ID (NCBI) 8887
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ86VP1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.

实验方案

Product Specific Protocols
WB protocol for TAX1BP1 antibody 60466-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols