验证数据展示
产品信息
60466-1-PBS targets TAX1BP1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | TAX1BP1 fusion protein Ag6279 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
别名 | TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10 |
计算分子量 | 91 kDa |
观测分子量 | 68 kDa, 85 kDa |
GenBank蛋白编号 | BC050358 |
基因名称 | TAX1BP1 |
Gene ID (NCBI) | 8887 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q86VP1 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.