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Conjugate
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Conjugate
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Conjugate
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TAX1BP1 Monoclonal antibody, PBS Only

TAX1BP1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H2D10

Cat no : 60466-1-PBS

Print datasheet

Synonyms

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10

验证数据展示

  • WB analysis using 60466-1-Ig (same clone as 60466-1-PBS)

    WB analysis using 60466-1-Ig (same clone as 60466-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60466-1-Ig (TAX1BP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60466-1-PBS in a different storage buffer formulation.

产品信息

60466-1-PBS targets TAX1BP1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen TAX1BP1 fusion protein Ag6279 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name Tax1 (human T-cell leukemia virus type I) binding protein 1
Synonyms TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10
Calculated Molecular Weight 91 kDa
Observed Molecular Weight68 kDa, 85 kDa
GenBank Accession NumberBC050358
Gene Symbol TAX1BP1
Gene ID (NCBI) 8887
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ86VP1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.