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TBC1D15 Polyclonal antibody, PBS Only

TBC1D15 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17252-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 17252-1-AP (same clone as 17252-1-PBS)

    WB analysis using 17252-1-AP (same clone as 17252-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17252-1-AP (TBC1D15 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17252-1-PBS in a different storage buffer formulation.

  • WB analysis using 17252-1-AP (same clone as 17252-1-PBS)

    WB analysis using 17252-1-AP (same clone as 17252-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17252-1-AP (TBC1D15 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17252-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 17252-1-AP (same clone as 17252-1-PBS)

    IF Staining of HeLa using 17252-1-AP (same clone as 17252-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using TBC1D15 antibody (17252-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 17252-1-PBS in a different storage buffer formulation.

产品信息

17252-1-PBS targets TBC1D15 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen TBC1D15 fusion protein Ag10625 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name TBC1 domain family, member 15
Synonyms
Calculated Molecular Weight 691 aa, 79 kDa
Observed Molecular Weight 79 kDa
GenBank Accession NumberBC028352
Gene Symbol TBC1D15
Gene ID (NCBI) 64786
RRIDAB_2878370
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TC07
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TBC1D15 is a highly conserved protein belonging to the TBC domain family and has similar functions to Rab-GAP. TBC1D15 is ubiquitously expressed and localized predominantly to the cytosol. TBC1D15 is a protein that contains a conserved Tre2/Bub2/Cdc16 (TBC) domain. TBC1D15 can serve as a mitochondrial Rab GTPase-activating protein (Rab-GAP) and influence autophagosome biogenesis and morphology downstream of Parkin activation. TBC1D15 can also control stem cell self-renewal when coupled with the Numb-p53 complex.